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Telotristat ethyl reverses myxomatous changes in mice mitral valves

RATIONALE: Myxomatous mitral valve degeneration is a common pathological manifestation of mitral valve regurgitation, with or without valvular prolapse. In addition to similarities between naturally occurring and serotonergic valve degeneration, an increasing body of evidence has recently suggested...

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Detalles Bibliográficos
Autores principales: Wang, Xinmei, Kuban-Johnston, Danielle, Lapuerta, Pablo, Lacerda, Carla M. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9386075/
https://www.ncbi.nlm.nih.gov/pubmed/35990981
http://dx.doi.org/10.3389/fcvm.2022.945672