Cargando…

Chemoproteomics reveals berberine directly binds to PKM2 to inhibit the progression of colorectal cancer

Colorectal cancer is one of the most serious tumors and berberine can inhibit the recurrence and transformation of colorectal adenoma into colorectal cancer. However, the direct binding target proteins of berberine in inhibiting colorectal cancer remain unclear. In this study, the chemical proteomic...

Descripción completa

Detalles Bibliográficos
Autores principales: Yan, Shi-Hai, Hu, Li-Mu, Hao, Xue-Hui, Liu, Jiang, Tan, Xi-Ying, Geng, Zhi-Rong, Ma, Jing, Wang, Zhi-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9386086/
https://www.ncbi.nlm.nih.gov/pubmed/35992091
http://dx.doi.org/10.1016/j.isci.2022.104773