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Chemoproteomics reveals berberine directly binds to PKM2 to inhibit the progression of colorectal cancer
Colorectal cancer is one of the most serious tumors and berberine can inhibit the recurrence and transformation of colorectal adenoma into colorectal cancer. However, the direct binding target proteins of berberine in inhibiting colorectal cancer remain unclear. In this study, the chemical proteomic...
Autores principales: | Yan, Shi-Hai, Hu, Li-Mu, Hao, Xue-Hui, Liu, Jiang, Tan, Xi-Ying, Geng, Zhi-Rong, Ma, Jing, Wang, Zhi-Lin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9386086/ https://www.ncbi.nlm.nih.gov/pubmed/35992091 http://dx.doi.org/10.1016/j.isci.2022.104773 |
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