Lipocalin-2 in neutrophils induces ferroptosis in septic cardiac dysfunction via increasing labile iron pool of cardiomyocytes

Cardiac dysfunction is a common complication of sepsis with high mortality. The present study was designed to identify the effect of neutrophil-derived lipocalin-2 (LCN2) in septic cardiac dysfunction (SCD) and its potential mechanism. Wild-type (WT) and LCN2-knockout (LCN2 KO) mice were peritoneall...

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Detalles Bibliográficos
Autores principales: Huang, Yuxue, Zhang, Ning, Xie, Cuiping, You, Yayu, Guo, Lei, Ye, Feiming, Xie, Xiaojie, Wang, Jian’an
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cardiovascular Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9386130/
https://www.ncbi.nlm.nih.gov/pubmed/35990970
http://dx.doi.org/10.3389/fcvm.2022.922534

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9386130/
https://www.ncbi.nlm.nih.gov/pubmed/35990970
http://dx.doi.org/10.3389/fcvm.2022.922534

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