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Association between CES1 rs2244613 and the pharmacokinetics and safety of dabigatran: Meta-analysis and quantitative trait loci analysis

OBJECTIVE: To date, the influence of the carboxylesterase 1 (CES1) rs2244613 genotype on the pharmacokinetics (PKs) and safety of dabigatran remains controversial. Hence, a systematic review was performed to study the association between CES1 rs2244613 genotype and the PKs and safety of dabigatran a...

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Detalles Bibliográficos
Autores principales: Li, Haobo, Zhang, Zhu, Weng, Haoyi, Qiu, Yuting, Zubiaur, Pablo, Zhang, Yu, Fan, Guohui, Yang, Peiran, Vuorinen, Anna-Leena, Zuo, Xianbo, Zhai, Zhenguo, Wang, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9386138/
https://www.ncbi.nlm.nih.gov/pubmed/35990949
http://dx.doi.org/10.3389/fcvm.2022.959916