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Cochlear ribbon synapse maturation requires Nlgn1 and Nlgn3

Hearing depends on precise synaptic transmission between cochlear inner hair cells and spiral ganglion neurons through afferent ribbon synapses. Neuroligins (Nlgns) facilitate synapse maturation in the brain, but they have gone unstudied in the cochlea. We report Nlgn3 and Nlgn1 knockout (KO) cochle...

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Detalles Bibliográficos
Autores principales: Ramirez, Miguel A., Ninoyu, Yuzuru, Miller, Cayla, Andrade, Leonardo R., Edassery, Seby, Bomba-Warczak, Ewa, Ortega, Briana, Manor, Uri, Rutherford, Mark A., Friedman, Rick A., Savas, Jeffrey N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9386149/
https://www.ncbi.nlm.nih.gov/pubmed/35992071
http://dx.doi.org/10.1016/j.isci.2022.104803