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Sacubitril/Valsartan Improves Progression of Early Diabetic Nephropathy in Rats Through Inhibition of NLRP3 Inflammasome Pathway

PURPOSE: Diabetic nephropathy (DN), a global disease, is the leading cause of end-stage renal disease. There is a lack of specific treatment for this disease, and early intervention in disease progression is essential. In this paper, we used a rat model of early diabetic nephropathy to explore the t...

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Detalles Bibliográficos
Autores principales: Pan, Yan, Liu, Lei, Yang, Huijuan, Chen, Weidong, Chen, Zheng, Xu, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9386175/
https://www.ncbi.nlm.nih.gov/pubmed/35992034
http://dx.doi.org/10.2147/DMSO.S366518