The impact of PrsA over-expression on the Bacillus subtilis transcriptome during fed-batch fermentation of alpha-amylase production

The production of the alpha-amylase (AMY) enzyme in Bacillus subtilis at a high rate leads to the accumulation of unfolded AMY, which causes secretion stress. The over-expression of the PrsA chaperone aids enzyme folding and reduces stress. To identify affected pathways and potential mechanisms invo...

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Detalles Bibliográficos
Autores principales: Geissler, Adrian S., Poulsen, Line D., Doncheva, Nadezhda T., Anthon, Christian, Seemann, Stefan E., González-Tortuero, Enrique, Breüner, Anne, Jensen, Lars J., Hjort, Carsten, Vinther, Jeppe, Gorodkin, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9386232/
https://www.ncbi.nlm.nih.gov/pubmed/35992681
http://dx.doi.org/10.3389/fmicb.2022.909493

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9386232/
https://www.ncbi.nlm.nih.gov/pubmed/35992681
http://dx.doi.org/10.3389/fmicb.2022.909493

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