I-κB kinase-ε deficiency improves doxorubicin-induced dilated cardiomyopathy by inhibiting the NF-κB pathway

Dilated cardiomyopathy (DCM) can lead to heart expansion and severe heart failure, but its specific pathogenesis is still elusive. In many cardiovascular diseases, I-κB kinase-ε (IKKε) has been recognized as a pro-inflammatory molecule. In this study, wild-type mice (WT, n = 14) and IKKε knockout mi...

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Detalles Bibliográficos
Autores principales: Liu, Yafeng, Xu, Yueyue, Yao, Yiwei, Cao, Yide, Chen, Ganyi, Cai, Yuchen, Chen, Wen, Chen, Xin, Qiu, Zhibing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9386238/
https://www.ncbi.nlm.nih.gov/pubmed/35991177
http://dx.doi.org/10.3389/fphys.2022.934899

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9386238/
https://www.ncbi.nlm.nih.gov/pubmed/35991177
http://dx.doi.org/10.3389/fphys.2022.934899

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