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I-κB kinase-ε deficiency improves doxorubicin-induced dilated cardiomyopathy by inhibiting the NF-κB pathway

Dilated cardiomyopathy (DCM) can lead to heart expansion and severe heart failure, but its specific pathogenesis is still elusive. In many cardiovascular diseases, I-κB kinase-ε (IKKε) has been recognized as a pro-inflammatory molecule. In this study, wild-type mice (WT, n = 14) and IKKε knockout mi...

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Detalles Bibliográficos
Autores principales:	Liu, Yafeng, Xu, Yueyue, Yao, Yiwei, Cao, Yide, Chen, Ganyi, Cai, Yuchen, Chen, Wen, Chen, Xin, Qiu, Zhibing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9386238/ https://www.ncbi.nlm.nih.gov/pubmed/35991177 http://dx.doi.org/10.3389/fphys.2022.934899

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