N6‐methyladenosine demethylase ALKBH5 suppresses colorectal cancer progression potentially by decreasing PHF20 mRNA methylation

BACKGROUND: As the most widespread mRNAs modification, N6‐methyladenosine (m(6)A) is dynamically and reversibly modulated by methyltransferases and demethylases. ALKBH5 is a major demethylase, and plays vital roles in the progression of cancers. However, the role and mechanisms of ALKBH5 in colorect...

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Detalles Bibliográficos
Autores principales: Zhang, Zhen, Wang, Ling, Zhao, Long, Wang, Quan, Yang, Changjiang, Zhang, Mengmeng, Wang, Bo, Jiang, Kewei, Ye, Yingjiang, Wang, Shan, Shen, Zhanlong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9386323/
https://www.ncbi.nlm.nih.gov/pubmed/35979628
http://dx.doi.org/10.1002/ctm2.940

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9386323/
https://www.ncbi.nlm.nih.gov/pubmed/35979628
http://dx.doi.org/10.1002/ctm2.940

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