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A simple protocol for the production of highly deuterated proteins for biophysical studies

Highly deuterated protein samples expand the biophysics and biological tool kit by providing, among other qualities, contrast matching in neutron diffraction experiments and reduction of dipolar spin interactions from normally protonated proteins in magnetic resonance studies, impacting both electro...

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Detalles Bibliográficos
Autores principales: Li, Jess, Byrd, R. Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9386462/
https://www.ncbi.nlm.nih.gov/pubmed/35835218
http://dx.doi.org/10.1016/j.jbc.2022.102253