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The conserved Mediator subunit cyclin C (CCNC) is required for brown adipocyte development and lipid accumulation

OBJECTIVE: Cyclin C (CCNC) is the most conserved subunit of the Mediator complex, which is an important transcription cofactor. Recently, we have found that CCNC facilitates brown adipogenesis in vitro by activating C/EBPα-dependent transcription. However, the role of CCNC in brown adipose tissue (B...

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Detalles Bibliográficos
Autores principales: Song, Ziyi, Xiaoli, Alus M., Li, Youlei, Siqin, Gerile, Wu, Tian, Strich, Randy, Pessin, Jeffrey E., Yang, Fajun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9386464/
https://www.ncbi.nlm.nih.gov/pubmed/35863637
http://dx.doi.org/10.1016/j.molmet.2022.101548