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Immunomodulatory effect and safety of TNF-α RNAi mediated by oral yeast microcapsules in rheumatoid arthritis therapy

Rheumatoid arthritis (RA) is a chronic autoimmune disease that requires long-term treatment and monitoring. Inhibition of inflammatory gene expression by gene therapy is a significant breakthrough in RA treatment, but the lack of a safe and effective gene delivery system hinders its application. Sin...

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Detalles Bibliográficos
Autores principales: Hu, Nan, Zhu, Li, Zhang, Li, Wang, Jing, Wang, Yanhua, Luo, Jing, He, Lan, Hao, Zhiming, Zhang, Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9386491/
https://www.ncbi.nlm.nih.gov/pubmed/35991628
http://dx.doi.org/10.1016/j.mtbio.2022.100384