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Idebenone does not inhibit disability progression in primary progressive MS

BACKGROUND: Multiple sclerosis (MS) is a chronic, immune-mediated neurodegenerative disorder of the central nervous system (CNS). While current MS therapies target the inflammatory processes, no treatment explicitly targets mitochondrial dysfunction and resulting axonal loss. Therefore, the aim of t...

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Detalles Bibliográficos
Autores principales: Kosa, Peter, Wu, Tianxia, Phillips, Jonathan, Leinonen, Mika, Masvekar, Ruturaj, Komori, Mika, Wichman, Alison, Sandford, Mary, Bielekova, Bibiana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9386688/
https://www.ncbi.nlm.nih.gov/pubmed/32784117
http://dx.doi.org/10.1016/j.msard.2020.102434