The ubiquitin-ligase TRAF6 and TGFβ type I receptor form a complex with Aurora kinase B contributing to mitotic progression and cytokinesis in cancer cells

BACKGROUND: Transforming growth factor β (TGFβ) is overexpressed in several advanced cancer types and promotes tumor progression. We have reported that the intracellular domain (ICD) of TGFβ receptor (TβR) I is cleaved by proteolytic enzymes in cancer cells, and then translocated to the nucleus in a...

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Detalles Bibliográficos
Autores principales: Song, Jie, Zhou, Yang, Yakymovych, Ihor, Schmidt, Alexej, Li, Chunyan, Heldin, Carl-Henrik, Landström, Maréne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9386726/
https://www.ncbi.nlm.nih.gov/pubmed/35853811
http://dx.doi.org/10.1016/j.ebiom.2022.104155

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9386726/
https://www.ncbi.nlm.nih.gov/pubmed/35853811
http://dx.doi.org/10.1016/j.ebiom.2022.104155

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