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Synthesis, Biological Evaluation, and In Silico Studies of Novel Coumarin-Based 4H,5H-pyrano[3,2-c]chromenes as Potent β-Glucuronidase and Carbonic Anhydrase Inhibitors

[Image: see text] The search for novel heterocyclic compounds with a natural product skeleton as potent enzyme inhibitors against clinical hits is our prime concern in this study. Here, a simple and facile two-step strategy has been designed to synthesize a series of novel coumarin-based dihydropyra...

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Detalles Bibliográficos
Autores principales: Arif, Nadia, Shafiq, Zahid, Mahmood, Khalid, Rafiq, Muhammad, Naz, Sadia, Shahzad, Sohail Anjum, Farooq, Umar, Bahkali, Ali H., Elgorban, Abdallah M., Yaqub, Muhammad, El-Gokha, Ahmed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9386806/
https://www.ncbi.nlm.nih.gov/pubmed/35990487
http://dx.doi.org/10.1021/acsomega.2c03528