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Solid-Phase Synthesis of an “Inaccessible” hGH-Derived Peptide Using a Pseudoproline Monomer and SIT-Protection for Cysteine

[Image: see text] The solid-phase peptide synthesis (SPPS) of the C-terminal sequence of hGH with one extra Tyr attached to its N-terminus (total of 16 residues with a disulfide bridge) has been accomplished for the first time by optimizing several synthetic parameters. First of all, the two Ser res...

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Detalles Bibliográficos
Autores principales: Manne, Srinivasa Rao, Chakraborty, Amit, Rustler, Karin, Bruckdorfer, Thomas, de la Torre, Beatriz G., Albericio, Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9386842/
https://www.ncbi.nlm.nih.gov/pubmed/35990446
http://dx.doi.org/10.1021/acsomega.2c03261