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Identification of individuals at risk for postoperative cognitive dysfunction (POCD)

Postoperative cognitive dysfunction (POCD) is common, occurring in around 10-54% of individuals within first few weeks after surgery. Although the majority of POCD is less commonly persistent later than 3 months following surgery, the condition increases length of stay (LOS), mortality and long-term...

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Autores principales: Yang, Xiao, Huang, Xinwei, Li, Min, Jiang, Yuan, Zhang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9386869/
https://www.ncbi.nlm.nih.gov/pubmed/35992893
http://dx.doi.org/10.1177/17562864221114356
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author Yang, Xiao
Huang, Xinwei
Li, Min
Jiang, Yuan
Zhang, Hong
author_facet Yang, Xiao
Huang, Xinwei
Li, Min
Jiang, Yuan
Zhang, Hong
author_sort Yang, Xiao
collection PubMed
description Postoperative cognitive dysfunction (POCD) is common, occurring in around 10-54% of individuals within first few weeks after surgery. Although the majority of POCD is less commonly persistent later than 3 months following surgery, the condition increases length of stay (LOS), mortality and long-term cognitive decline, raising the need for a broad screening to identify individuals at risk for POCD during the perioperative period. In this narrative review, we summarize preoperative, intraoperative and postoperative risk factors for POCD reported in last 5 years and discuss neuropsychological tools and potential biomarkers and time points for assessment that might be suitable for clinical use. We aim to provide crucial information for developing a strategy of routine screening for POCD, which may assist with better identification of at-risk individuals for early interventions. Very importantly, the utilization of a standardized strategy may also allow higher consistency and comparability across different studies.
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spelling pubmed-93868692022-08-19 Identification of individuals at risk for postoperative cognitive dysfunction (POCD) Yang, Xiao Huang, Xinwei Li, Min Jiang, Yuan Zhang, Hong Ther Adv Neurol Disord Review Postoperative cognitive dysfunction (POCD) is common, occurring in around 10-54% of individuals within first few weeks after surgery. Although the majority of POCD is less commonly persistent later than 3 months following surgery, the condition increases length of stay (LOS), mortality and long-term cognitive decline, raising the need for a broad screening to identify individuals at risk for POCD during the perioperative period. In this narrative review, we summarize preoperative, intraoperative and postoperative risk factors for POCD reported in last 5 years and discuss neuropsychological tools and potential biomarkers and time points for assessment that might be suitable for clinical use. We aim to provide crucial information for developing a strategy of routine screening for POCD, which may assist with better identification of at-risk individuals for early interventions. Very importantly, the utilization of a standardized strategy may also allow higher consistency and comparability across different studies. SAGE Publications 2022-08-16 /pmc/articles/PMC9386869/ /pubmed/35992893 http://dx.doi.org/10.1177/17562864221114356 Text en © The Author(s), 2022 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Review
Yang, Xiao
Huang, Xinwei
Li, Min
Jiang, Yuan
Zhang, Hong
Identification of individuals at risk for postoperative cognitive dysfunction (POCD)
title Identification of individuals at risk for postoperative cognitive dysfunction (POCD)
title_full Identification of individuals at risk for postoperative cognitive dysfunction (POCD)
title_fullStr Identification of individuals at risk for postoperative cognitive dysfunction (POCD)
title_full_unstemmed Identification of individuals at risk for postoperative cognitive dysfunction (POCD)
title_short Identification of individuals at risk for postoperative cognitive dysfunction (POCD)
title_sort identification of individuals at risk for postoperative cognitive dysfunction (pocd)
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9386869/
https://www.ncbi.nlm.nih.gov/pubmed/35992893
http://dx.doi.org/10.1177/17562864221114356
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