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Identification of individuals at risk for postoperative cognitive dysfunction (POCD)
Postoperative cognitive dysfunction (POCD) is common, occurring in around 10-54% of individuals within first few weeks after surgery. Although the majority of POCD is less commonly persistent later than 3 months following surgery, the condition increases length of stay (LOS), mortality and long-term...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9386869/ https://www.ncbi.nlm.nih.gov/pubmed/35992893 http://dx.doi.org/10.1177/17562864221114356 |
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author | Yang, Xiao Huang, Xinwei Li, Min Jiang, Yuan Zhang, Hong |
author_facet | Yang, Xiao Huang, Xinwei Li, Min Jiang, Yuan Zhang, Hong |
author_sort | Yang, Xiao |
collection | PubMed |
description | Postoperative cognitive dysfunction (POCD) is common, occurring in around 10-54% of individuals within first few weeks after surgery. Although the majority of POCD is less commonly persistent later than 3 months following surgery, the condition increases length of stay (LOS), mortality and long-term cognitive decline, raising the need for a broad screening to identify individuals at risk for POCD during the perioperative period. In this narrative review, we summarize preoperative, intraoperative and postoperative risk factors for POCD reported in last 5 years and discuss neuropsychological tools and potential biomarkers and time points for assessment that might be suitable for clinical use. We aim to provide crucial information for developing a strategy of routine screening for POCD, which may assist with better identification of at-risk individuals for early interventions. Very importantly, the utilization of a standardized strategy may also allow higher consistency and comparability across different studies. |
format | Online Article Text |
id | pubmed-9386869 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-93868692022-08-19 Identification of individuals at risk for postoperative cognitive dysfunction (POCD) Yang, Xiao Huang, Xinwei Li, Min Jiang, Yuan Zhang, Hong Ther Adv Neurol Disord Review Postoperative cognitive dysfunction (POCD) is common, occurring in around 10-54% of individuals within first few weeks after surgery. Although the majority of POCD is less commonly persistent later than 3 months following surgery, the condition increases length of stay (LOS), mortality and long-term cognitive decline, raising the need for a broad screening to identify individuals at risk for POCD during the perioperative period. In this narrative review, we summarize preoperative, intraoperative and postoperative risk factors for POCD reported in last 5 years and discuss neuropsychological tools and potential biomarkers and time points for assessment that might be suitable for clinical use. We aim to provide crucial information for developing a strategy of routine screening for POCD, which may assist with better identification of at-risk individuals for early interventions. Very importantly, the utilization of a standardized strategy may also allow higher consistency and comparability across different studies. SAGE Publications 2022-08-16 /pmc/articles/PMC9386869/ /pubmed/35992893 http://dx.doi.org/10.1177/17562864221114356 Text en © The Author(s), 2022 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Review Yang, Xiao Huang, Xinwei Li, Min Jiang, Yuan Zhang, Hong Identification of individuals at risk for postoperative cognitive dysfunction (POCD) |
title | Identification of individuals at risk for postoperative cognitive dysfunction (POCD) |
title_full | Identification of individuals at risk for postoperative cognitive dysfunction (POCD) |
title_fullStr | Identification of individuals at risk for postoperative cognitive dysfunction (POCD) |
title_full_unstemmed | Identification of individuals at risk for postoperative cognitive dysfunction (POCD) |
title_short | Identification of individuals at risk for postoperative cognitive dysfunction (POCD) |
title_sort | identification of individuals at risk for postoperative cognitive dysfunction (pocd) |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9386869/ https://www.ncbi.nlm.nih.gov/pubmed/35992893 http://dx.doi.org/10.1177/17562864221114356 |
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