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From rare disorders of immunity to common determinants of infection: Following the mechanistic thread

The immense interindividual clinical variability during any infection is a long-standing enigma. Inborn errors of IFN-γ and IFN-α/β immunity underlying rare infections with weakly virulent mycobacteria and seasonal influenza virus have inspired studies of two common infections: tuberculosis and COVI...

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Detalles Bibliográficos
Autores principales: Casanova, Jean-Laurent, Abel, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9386946/
https://www.ncbi.nlm.nih.gov/pubmed/35985287
http://dx.doi.org/10.1016/j.cell.2022.07.004