HORNBILL: a phase I/IIa trial examining the safety, tolerability and early response of BI 764524 in patients with diabetic retinopathy and diabetic macular ischaemia—rationale, study design and protocol

BACKGROUND: Diabetic macular ischaemia (DMI) is a complication of diabetic retinopathy that leads to irreversible vision loss. DMI is characterised by reduced retinal vessel density and enlargement of the foveal avascular zone (FAZ). Despite its clinical burden, there is no formal consensus on the d...

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Detalles Bibliográficos
Autores principales: Chong, Victor, Nguyen, Quan Dong, Sepah, Yasir, Giani, Andrea, Pearce, Elizabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9386971/
https://www.ncbi.nlm.nih.gov/pubmed/35978329
http://dx.doi.org/10.1186/s13063-022-06527-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9386971/
https://www.ncbi.nlm.nih.gov/pubmed/35978329
http://dx.doi.org/10.1186/s13063-022-06527-y

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