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Mesenchymal stem cells protect against TBI-induced pyroptosis in vivo and in vitro through TSG-6

BACKGROUND: Pyroptosis, especially microglial pyroptosis, may play an important role in central nervous system pathologies, including traumatic brain injury (TBI). Transplantation of mesenchymal stem cells (MSCs), such as human umbilical cord MSCs (hUMSCs), has been a focus of brain injury treatment...

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Detalles Bibliográficos
Autores principales: Feng, Zhiming, Hua, Shiting, Li, Wangan, Han, Jianbang, Li, Feng, Chen, Haijia, Zhang, Zhongfei, Xie, Yu, Ouyang, Qian, Zou, Xiaoxiong, Liu, Zhizheng, Li, Cong, Huang, Sixian, Lai, Zelin, Cai, Xiaolin, Cai, Yingqian, Zou, Yuxi, Tang, Yanping, Jiang, Xiaodan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9387023/
https://www.ncbi.nlm.nih.gov/pubmed/35982465
http://dx.doi.org/10.1186/s12964-022-00931-2