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The effect of aging on the repeated-dose liver micronucleus assay using diethylnitrosamine
BACKGROUND: The repeated-dose liver micronucleus (RDLMN) assay has been well-developed and applied because of its simplicity and the ease of integration into general toxicity studies which is the preferred method from the 3R’s point of view. In this assay, we observed micronucleated hepatocytes whic...
Autores principales: | Satomoto, Kensuke, Suzuki, Isamu, Mita, Koji, Wakita, Atsushi, Yamagata, Hiroshi, Mitsumoto, Tatsuya, Hamada, Shuichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9387043/ https://www.ncbi.nlm.nih.gov/pubmed/35982479 http://dx.doi.org/10.1186/s41021-022-00250-5 |
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