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Gingko biloba-inspired lactone prevents osteoarthritis by activating the AMPK-SIRT1 signaling pathway

BACKGROUND: Uncoupled extracellular matrix (ECM) causes cartilage degeneration and osteoarthritis (OA) by suppressing the synthesis and activating the degradation of ECM components. Gingko biloba is a natural Chinese herb with a variety of biological functions; however, the extent to which it can pr...

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Detalles Bibliográficos
Autores principales: Zhao, Zhijian, Liu, Yang, Lu, Yingjie, Hou, Mingzhuang, Shen, Xu, Yang, Huilin, Shi, Qin, Zhang, Yijian, He, Fan, Zhu, Xuesong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9387049/
https://www.ncbi.nlm.nih.gov/pubmed/35982488
http://dx.doi.org/10.1186/s13075-022-02890-y