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Mitochondrial Imbalance of Trypanosoma cruzi Induced by the Marine Alkaloid 6-Bromo-2′-de-N-Methylaplysinopsin

[Image: see text] Chagas disease, caused by Trypanosoma cruzi, affects seven million people worldwide and lacks effective treatments. Using bioactivity-guided fractionation, NMR, and electrospray ionization-high resolution mass spectrometry (ESI-HRMS) spectral analysis, the indole alkaloid 6-bromo-2...

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Detalles Bibliográficos
Autores principales: Romanelli, Maiara M., Amaral, Maiara, Thevenard, Fernanda, Santa Cruz, Lucas M., Regasini, Luis O., Migotto, Alvaro E., Lago, João Henrique G., Tempone, Andre G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9387129/
https://www.ncbi.nlm.nih.gov/pubmed/35990437
http://dx.doi.org/10.1021/acsomega.2c03395