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Transmissible SARS-CoV-2 variants with resistance to clinical protease inhibitors

Vaccines and drugs have helped reduce disease severity and blunt the spread of SARS-CoV-2. However, ongoing virus transmission, continuous evolution, and increasing selective pressures have the potential to yield viral variants capable of resisting these interventions. Here, we investigate the susce...

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Detalles Bibliográficos
Autores principales: Moghadasi, Seyed Arad, Heilmann, Emmanuel, Khalil, Ahmed Magdy, Nnabuife, Christina, Kearns, Fiona L., Ye, Chengjin, Moraes, Sofia N., Costacurta, Francesco, Esler, Morgan A., Aihara, Hideki, von Laer, Dorothee, Martinez-Sobrido, Luis, Palzkill, Timothy, Amaro, Rommie E., Harris, Reuben S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9387136/
https://www.ncbi.nlm.nih.gov/pubmed/35982678
http://dx.doi.org/10.1101/2022.08.07.503099