Immune Heterogeneity and Epistasis Explain Punctuated Evolution of SARS-CoV-2

Identifying drivers of viral diversity is key to understanding the evolutionary as well as epidemiological dynamics of the COVID-19 pandemic. Using rich viral genomic data sets, we show that periods of steadily rising diversity have been punctuated by sudden, enormous increases followed by similarly...

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Detalles Bibliográficos
Autores principales: Nielsen, Bjarke Frost, Li, Yimei, Sneppen, Kim, Simonsen, Lone, Viboud, Cécile, Levin, Simon A., Grenfell, Bryan T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9387145/
https://www.ncbi.nlm.nih.gov/pubmed/35982659
http://dx.doi.org/10.1101/2022.07.27.22278129

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9387145/
https://www.ncbi.nlm.nih.gov/pubmed/35982659
http://dx.doi.org/10.1101/2022.07.27.22278129

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