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Immune Heterogeneity and Epistasis Explain Punctuated Evolution of SARS-CoV-2
Identifying drivers of viral diversity is key to understanding the evolutionary as well as epidemiological dynamics of the COVID-19 pandemic. Using rich viral genomic data sets, we show that periods of steadily rising diversity have been punctuated by sudden, enormous increases followed by similarly...
Autores principales: | Nielsen, Bjarke Frost, Li, Yimei, Sneppen, Kim, Simonsen, Lone, Viboud, Cécile, Levin, Simon A., Grenfell, Bryan T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9387145/ https://www.ncbi.nlm.nih.gov/pubmed/35982659 http://dx.doi.org/10.1101/2022.07.27.22278129 |
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