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Viral Kinetics of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Omicron Infection in mRNA-Vaccinated Individuals Treated and Not Treated with Nirmatrelvir-Ritonavir

We measured viral kinetics of SARS-CoV-2 Omicron infection in 36 mRNA-vaccinated individuals, 11 of whom were treated with nirmatrelvir-ritonavir (NMV-r). We found that NMV-r was associated with greater incidence of viral rebound compared to no treatment. For those that did not rebound, NMV-r signif...

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Detalles Bibliográficos
Autores principales: Dai, Eric Y., Lee, Kannon A., Nathanson, Audrey B., Leonelli, Ariana T., Petros, Brittany A., Brock-Fisher, Taylor, Dobbins, Sabrina T., MacInnis, Bronwyn L., Capone, Amelia, Littlehale, Nancy, Boucau, Julie, Marino, Caitlin, Barczak, Amy K., Sabeti, Pardis C., Springer, Michael, Stephenson, Kathryn E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9387148/
https://www.ncbi.nlm.nih.gov/pubmed/35982651
http://dx.doi.org/10.1101/2022.08.04.22278378