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Similar protein segments shared between domains of different evolutionary lineages

The emergence of novel proteins, beyond these that can be readily made by duplication and recombination of preexisting domains, is elusive. De novo emergence from random sequences is unlikely because the vast majority of random chains would not even fold, let alone function. An alternative explanati...

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Detalles Bibliográficos
Autores principales: Qiu, Kaiyu, Ben‐Tal, Nir, Kolodny, Rachel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9387206/
https://www.ncbi.nlm.nih.gov/pubmed/36040261
http://dx.doi.org/10.1002/pro.4407