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Elevated c-di-GMP Levels and Expression of the Type III Secretion System Promote Corneal Infection by Pseudomonas aeruginosa

Pseudomonas aeruginosa is generally believed to establish biofilm-associated infections under the regulation of the secondary messenger c-di-GMP. To evaluate P. aeruginosa biofilm physiology during ocular infections, comparative transcriptomic analysis was performed on wild-type P. aeruginosa PAO1,...

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Detalles Bibliográficos
Autores principales: Yam, Joey Kuok Hoong, Aung, Thet Tun, Chua, Song Lin, Cheng, Yingying, Kohli, Gurjeet Singh, Zhou, Jianuan, Constancias, Florentin, Liu, Yang, Cai, Zhao, Salido, May Margarette Santillan, Drautz-Moses, Daniela I., Rice, Scott A., Schuster, Stephan Christoph, Boo, Zhao Zhi, Wu, Bin, Kjelleberg, Staffan, Tolker-Nielsen, Tim, Lakshminarayanan, Rajamani, Beuerman, Roger W., Yang, Liang, Givskov, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9387266/
https://www.ncbi.nlm.nih.gov/pubmed/35913171
http://dx.doi.org/10.1128/iai.00061-22