Bilosomes as a promising nanoplatform for oral delivery of an alkaloid nutraceutical: improved pharmacokinetic profile and snowballed hypoglycemic effect in diabetic rats

Diabetes mellitus is a life-threatening metabolic disease. At the moment, there is no effective treatment available to combat it. In this study, we aimed to develop berberine-loaded bilosomes (BER-BLS) to boost the oral bioavailability and therapeutic efficacy of berberine, a natural antidiabetic me...

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Detalles Bibliográficos
Autores principales: Elkomy, Mohammed H., Eid, Hussein M., Elmowafy, Mohammed, Shalaby, Khaled, Zafar, Ameeduzzafar, Abdelgawad, Mohamed A., Rateb, Mostafa E., Ali, Mohammed R.A., Alsalahat, Izzeddin, Abou-Taleb, Heba A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9387316/
https://www.ncbi.nlm.nih.gov/pubmed/35975320
http://dx.doi.org/10.1080/10717544.2022.2110997

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9387316/
https://www.ncbi.nlm.nih.gov/pubmed/35975320
http://dx.doi.org/10.1080/10717544.2022.2110997

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