Targeting PIM2 by JP11646 results in significant antitumor effects in solid tumors

Proviral integration of Moloney virus 2 (PIM2) is a pro-survival factor of cancer cells and a possible therapeutic target in hematological malignancies. However, the attempts at inhibiting PIM2 have yielded underwhelming results in early clinical trials on hematological malignancies. Recently, a nov...

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Detalles Bibliográficos
Autores principales: Katsuta, Eriko, Gil-Moore, Malgorzata, Moore, Justine, Yousif, Mohamed, Adjei, Alex A., Ding, Yi, Caserta, Justin, Baldino, Carmen M., Lee, Kelvin P., Gelman, Irwin H., Takabe, Kazuaki, Opyrchal, Mateusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9387562/
https://www.ncbi.nlm.nih.gov/pubmed/35920189
http://dx.doi.org/10.3892/ijo.2022.5404

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9387562/
https://www.ncbi.nlm.nih.gov/pubmed/35920189
http://dx.doi.org/10.3892/ijo.2022.5404

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