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Imaging of antitubercular dimeric boronic acids at the mycobacterial cell surface by click-probe capture

Dimeric boronic acids kill Mycobacterium tuberculosis (Mtb) by targeting mycobacterial specific extracellular glycans, removing the requirement for a therapeutic agent to permeate the complex cell envelope. Here we report the successful development and use of new ‘clickable’ boronic acid probes as a...

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Detalles Bibliográficos
Autores principales: Guy, Collette S., Tomás, Ruben M. F., Tang, Qiao, Gibson, Matthew I., Fullam, Elizabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9387567/
https://www.ncbi.nlm.nih.gov/pubmed/35917119
http://dx.doi.org/10.1039/d2cc02407a