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Chimeric Antigen Receptor T Cells Targeting Cell Surface GRP78 to Eradicate Acute Myeloid Leukemia

Acute myeloid leukemia (AML) is a serious, life-threatening hematological malignancy. The treatment outcome of relapsed or refractory AML patients remains dismal, and new treatment options are needed. Chimeric antigen receptor (CAR) T cells have been successful in improving the prognosis for B-linea...

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Detalles Bibliográficos
Autores principales: Yu, Wei, Zhang, Hang, Yuan, Yuncang, Tang, Jie, Chen, Xinchuan, Liu, Ting, Zhao, Xudong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9387679/
https://www.ncbi.nlm.nih.gov/pubmed/35990606
http://dx.doi.org/10.3389/fcell.2022.928140