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Characterization of Aldosterone-producing Cell Cluster (APCC) at Single-cell Resolution

CONTEXT: The adrenal cortex consists of zona glomerulosa (ZG), fasciculata (ZF), and reticularis. Aldosterone-producing cell clusters (APCCs) that strongly express aldosterone synthase (CYP11B2) are frequently found in adult adrenals and harbor somatic mutations that are also detected in aldosterone...

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Detalles Bibliográficos
Autores principales: Iwahashi, Norifusa, Umakoshi, Hironobu, Seki, Tsugio, Gomez-Sanchez, Celso E, Mukai, Kuniaki, Suematsu, Makoto, Umezawa, Yuta, Oya, Mototsugu, Kosaka, Takeo, Seki, Masahide, Suzuki, Yutaka, Horiuchi, Yutaka, Ogawa, Yoshihiro, Nishimoto, Koshiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9387688/
https://www.ncbi.nlm.nih.gov/pubmed/35796577
http://dx.doi.org/10.1210/clinem/dgac394