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Sodium phosphate cotransporter 2a inhibitors: potential therapeutic uses

Targeting sodium phosphate cotransporter 2a (Npt2a) offers a novel strategy for treating hyperphosphatemia in chronic kidney disease (CKD). Here we review recent studies on the efficacy of Npt2a inhibition, its plasma phosphate (P(i))-lowering effects, as well as potential “off-target” beneficial ef...

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Detalles Bibliográficos
Autores principales: Xue, Jianxiang, Thomas, Linto, Dominguez Rieg, Jessica A., Rieg, Timo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9387751/
https://www.ncbi.nlm.nih.gov/pubmed/35894284
http://dx.doi.org/10.1097/MNH.0000000000000828