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Murine precursors to type 1 conventional dendritic cells induce tumor cytotoxicity and exhibit activated PD-1/PD-L1 pathway

The immediate precursor to murine type 1 conventional DCs (cDC1s) has recently been established and named “pre-cDC1s”. Mature CD8α+ cDC1s are recognized for suppressing graft-versus-host disease (GvHD) while promoting graft-versus-leukemia (GvL), however pre-cDC1s have not previously been investigat...

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Detalles Bibliográficos
Autores principales: Molina, Megan S., Hoffman, Emely A., Stokes, Jessica, Kummet, Nicole, Simpson, Richard J., Katsanis, Emmanuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9387840/
https://www.ncbi.nlm.nih.gov/pubmed/35980974
http://dx.doi.org/10.1371/journal.pone.0273075