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Screening of drug candidates against Endothelin-1 to treat hypertension using computational based approaches: Molecular docking and dynamics simulation

Hypertension (HTN) is a major risk factor for cardiovascular and renal diseases, cerebrovascular accidents (CVA) and a prime underlying cause of worldwide morbidity and mortality. Hypertension is a complex condition and a strong interplay of multiple genetic, epigenetic and environmental factors is...

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Detalles Bibliográficos
Autores principales: Fatima, Israr, Ihsan, Hamza, Masoud, Muhammad Shareef, Kalsoom, Saeeda, Aslam, Sidra, Rehman, Abdur, Ashfaq, Usman Ali, Qasim, Muhammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9387841/
https://www.ncbi.nlm.nih.gov/pubmed/35981003
http://dx.doi.org/10.1371/journal.pone.0269739