Immune hyporeactivity to bacteria and multiple TLR-ligands, yet no response to checkpoint inhibition in patients just after meeting Sepsis-3 criteria

RATIONALE: The immune profile of sepsis patients is incompletely understood and hyperinflammation and hypoinflammation may occur concurrently or sequentially. Immune checkpoint inhibition (ICI) may counter hypoinflammation but effects are uncertain. We tested the reactivity of septic whole blood to...

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Detalles Bibliográficos
Autores principales: Bick, Alexandra, Buys, Willem, Engler, Andrea, Madel, Rabea, Atia, Mazen, Faro, Francesca, Westendorf, Astrid M., Limmer, Andreas, Buer, Jan, Herbstreit, Frank, Kirschning, Carsten J., Peters, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9387870/
https://www.ncbi.nlm.nih.gov/pubmed/35981050
http://dx.doi.org/10.1371/journal.pone.0273247

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9387870/
https://www.ncbi.nlm.nih.gov/pubmed/35981050
http://dx.doi.org/10.1371/journal.pone.0273247

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