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Response to treatment with an ALK-TKI in a patient with advanced lung adenocarcinoma with concurrent ALK fusion and high PD-L1 expression: A case report

RATIONALE: Previous studies have shown that PD-L1 TPS ≥50% in lung cancer rarely overlaps with driver oncogenes such as epidermal growth factor receptor and anaplastic lymphoma kinase (ALK). The initial gene detection of the patient in this study showed ALK fusion combined with high expression of PD...

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Detalles Bibliográficos
Autores principales: Zhang, Yaping, Fang, Hongming, Hong, Jianfeng, Wang, Xiaoyan, Wang, Hui, Pan, Guoqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9387991/
https://www.ncbi.nlm.nih.gov/pubmed/35984185
http://dx.doi.org/10.1097/MD.0000000000030094