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IGF-1 receptor regulates upward firing rate homeostasis via the mitochondrial calcium uniporter

Regulation of firing rate homeostasis constitutes a fundamental property of central neural circuits. While intracellular Ca(2+) has long been hypothesized to be a feedback control signal, the molecular machinery enabling a network-wide homeostatic response remains largely unknown. We show that delet...

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Detalles Bibliográficos
Autores principales: Katsenelson, Maxim, Shapira, Ilana, Abbas, Eman, Jevdokimenko, Kristina, Styr, Boaz, Ruggiero, Antonella, Aïd, Saba, Fornasiero, Eugenio F., Holzenberger, Martin, Rizzoli, Silvio O., Slutsky, Inna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9388073/
https://www.ncbi.nlm.nih.gov/pubmed/35943986
http://dx.doi.org/10.1073/pnas.2121040119