Structural insights into the human PA28–20S proteasome enabled by efficient tagging and purification of endogenous proteins

The ability to produce folded and functional proteins is a necessity for structural biology and many other biological sciences. This task is particularly challenging for numerous biomedically important targets in human cells, including membrane proteins and large macromolecular assemblies, hampering...

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Detalles Bibliográficos
Autores principales: Zhao, Jianhua, Makhija, Suraj, Zhou, Chenyu, Zhang, Hanxiao, Wang, YongQiang, Muralidharan, Monita, Huang, Bo, Cheng, Yifan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9388094/
https://www.ncbi.nlm.nih.gov/pubmed/35858375
http://dx.doi.org/10.1073/pnas.2207200119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9388094/
https://www.ncbi.nlm.nih.gov/pubmed/35858375
http://dx.doi.org/10.1073/pnas.2207200119

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