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trim-21 promotes proteasomal degradation of CED-1 for apoptotic cell clearance in C. elegans

The phagocytic receptor CED-1 mediates apoptotic cell recognition by phagocytic cells, enabling cell corpse clearance in Caenorhabditis elegans. Whether appropriate levels of CED-1 are maintained for executing the engulfment function remains unknown. Here, we identified the C. elegans E3 ubiquitin l...

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Detalles Bibliográficos
Autores principales: Yuan, Lei, Li, Peiyao, Jing, Huiru, Zheng, Qian, Xiao, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9388098/
https://www.ncbi.nlm.nih.gov/pubmed/35929733
http://dx.doi.org/10.7554/eLife.76436