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Balanced control of thermogenesis by nuclear receptor corepressors in brown adipose tissue

Brown adipose tissue (BAT) is a key thermogenic organ whose expression of uncoupling protein 1 (UCP1) and ability to maintain body temperature in response to acute cold exposure require histone deacetylase 3 (HDAC3). HDAC3 exists in tight association with nuclear receptor corepressors (NCoRs) NCoR1...

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Detalles Bibliográficos
Autores principales: Richter, Hannah J., Hauck, Amy K., Batmanov, Kirill, Inoue, Shin-Ichi, So, Bethany N., Kim, Mindy, Emmett, Matthew J., Cohen, Ronald N., Lazar, Mitchell A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9388101/
https://www.ncbi.nlm.nih.gov/pubmed/35939699
http://dx.doi.org/10.1073/pnas.2205276119