Reciprocal interplay between OTULIN–LUBAC determines genotoxic and inflammatory NF-κB signal responses

Targeting nuclear factor-kappa B (NF-κB) represents a highly viable strategy against chemoresistance in cancers as well as cell death. Ubiquitination, including linear ubiquitination mediated by the linear ubiquitin chain assembly complex (LUBAC), is emerging as a crucial mechanism of overactivated...

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Detalles Bibliográficos
Autores principales: Li, Mingqi, Li, Ling, Asemota, Sarah, Kakhniashvili, David, Narayanan, Ramesh, Wang, Xusheng, Liao, Francesca-Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9388121/
https://www.ncbi.nlm.nih.gov/pubmed/35939695
http://dx.doi.org/10.1073/pnas.2123097119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9388121/
https://www.ncbi.nlm.nih.gov/pubmed/35939695
http://dx.doi.org/10.1073/pnas.2123097119

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