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Reciprocal interplay between OTULIN–LUBAC determines genotoxic and inflammatory NF-κB signal responses
Targeting nuclear factor-kappa B (NF-κB) represents a highly viable strategy against chemoresistance in cancers as well as cell death. Ubiquitination, including linear ubiquitination mediated by the linear ubiquitin chain assembly complex (LUBAC), is emerging as a crucial mechanism of overactivated...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9388121/ https://www.ncbi.nlm.nih.gov/pubmed/35939695 http://dx.doi.org/10.1073/pnas.2123097119 |