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Elevated Myl9 reflects the Myl9-containing microthrombi in SARS-CoV-2–induced lung exudative vasculitis and predicts COVID-19 severity

The mortality of coronavirus disease 2019 (COVID-19) is strongly correlated with pulmonary vascular pathology accompanied by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection–triggered immune dysregulation and aberrant activation of platelets. We combined histological analyses u...

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Detalles Bibliográficos
Autores principales: Iwamura, Chiaki, Hirahara, Kiyoshi, Kiuchi, Masahiro, Ikehara, Sanae, Azuma, Kazuhiko, Shimada, Tadanaga, Kuriyama, Sachiko, Ohki, Syota, Yamamoto, Emiri, Inaba, Yosuke, Shiko, Yuki, Aoki, Ami, Kokubo, Kota, Hirasawa, Rui, Hishiya, Takahisa, Tsuji, Kaori, Nagaoka, Tetsutaro, Ishikawa, Satoru, Kojima, Akira, Mito, Haruki, Hase, Ryota, Kasahara, Yasunori, Kuriyama, Naohide, Tsukamoto, Tetsuya, Nakamura, Sukeyuki, Urushibara, Takashi, Kaneda, Satoru, Sakao, Seiichiro, Tobiume, Minoru, Suzuki, Yoshio, Tsujiwaki, Mitsuhiro, Kubo, Terufumi, Hasegawa, Tadashi, Nakase, Hiroshi, Nishida, Osamu, Takahashi, Kazuhisa, Baba, Komei, Iizumi, Yoko, Okazaki, Toshiya, Kimura, Motoko Y., Yoshino, Ichiro, Igari, Hidetoshi, Nakajima, Hiroshi, Suzuki, Takuji, Hanaoka, Hideki, Nakada, Taka-aki, Ikehara, Yuzuru, Yokote, Koutaro, Nakayama, Toshinori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9388124/
https://www.ncbi.nlm.nih.gov/pubmed/35895716
http://dx.doi.org/10.1073/pnas.2203437119