Structural basis of higher order oligomerization of KSHV inhibitor of cGAS

Kaposi's sarcoma–associated herpesvirus (KSHV) inhibitor of cyclic GMP–AMP synthase (cGAS) (KicGAS) encoded by ORF52 is a conserved major tegument protein of KSHV and the first reported viral inhibitor of cGAS. In our previous study, we found that KicGAS is highly oligomerized in solution and t...

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Detalles Bibliográficos
Autores principales: Bhowmik, Debipreeta, Tian, Yuan, Wang, Bing, Zhu, Fanxiu, Yin, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9388135/
https://www.ncbi.nlm.nih.gov/pubmed/35939686
http://dx.doi.org/10.1073/pnas.2200285119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9388135/
https://www.ncbi.nlm.nih.gov/pubmed/35939686
http://dx.doi.org/10.1073/pnas.2200285119

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