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Cross-linker design determines microtubule network organization by opposing motors

During cell division, cross-linking motors determine the architecture of the spindle, a dynamic microtubule network that segregates the chromosomes in eukaryotes. It is unclear how motors with opposite directionality coordinate to drive both contractile and extensile behaviors in the spindle. Partic...

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Detalles Bibliográficos
Autores principales: Henkin, Gil, Chew, Wei-Xiang, Nédélec, François, Surrey, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9388136/
https://www.ncbi.nlm.nih.gov/pubmed/35960844
http://dx.doi.org/10.1073/pnas.2206398119